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Quattroflow Single-Use Quaternary Diaphragm Pumps for RFC Systems

Contributed by: PumpScout Staff

Quattroflow is a leading brand from Almatec, which is part of Dover’s Pump Solutions Group (PSG). Quattroflow manufactures positive displacement quaternary diaphragm pumps for industries that rely on gentle displacement, reliability, product safety, purity, and cleanability such as the pharmaceutical and biopharmaceutical industries.

Quattroflow’s full line of single-use quaternary diaphragm pumps are ideal for use in Radial Flow Chromatography (RFC) systems that are used to absorb and purify Active Pharmaceutical Ingredients (API) during the “downstream” stage of biopharmaceutical production.

RFC differs from typical chromatography systems by utilizing a vertical rather than horizontal column design. In this system, chromatographic media (usually a resin) is wrapped around the vertical chromatography cylinder, reducing the system’s footprint and weight without a decrease in quality of purification and fractionation of the API that is required.

Proper packing of the chromatography media (resin) is paramount to optimizing RFC column performance. Quattroflow pumps are available in QF-150, QF-1200, QF-4400, QF-5050 and QF20K sizes and feature a four-piston/four-diaphragm method of design and operation that delivers low pulsation, gentle product handling, a large turndown ratio, high flow-rate accuracy, low noise, and a compact construction.

All Quattroflow quaternary diaphragm pump models are available as single-use configurations with replaceable plastic heads. This eliminates the need for time consuming cleaning between batches, increasing the product’s speed-to-market capabilities. Due to patent window considerations, this is a crucial feature, ensuring maximum product availability during the patented time frame.

Source: PSG Dover